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Molecular diversity and combinatorial chemistry libraries and drug discovery by

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Published by American Chemical Society in Washington, DC .
Written in English

Subjects:

  • Combinatorial chemistry -- Congresses.,
  • Drugs -- Design -- Congresses.

Book details:

Edition Notes

StatementIrwin M. Chaiken, Kim D. Janda, [editors].
SeriesConference proceeding series, Conference proceedings series (American Chemical Society)
ContributionsChaiken, Irwin M., Janda, Kim D., 1957-, Cambridge Healthtech Institute.
Classifications
LC ClassificationsRS419 .M65 1996
The Physical Object
Paginationix, 328 p. :
Number of Pages328
ID Numbers
Open LibraryOL982766M
ISBN 100841234507
LC Control Number96020429

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Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework . Molecular Diversity and Combinatorial Chemistry: Libraries and Drug Discovery (ACS Conference Proceedings): Medicine & Health Science Books @ mat: Hardcover. Use of Combinatorial Libraries in the Discovery and Development of Novel Anti-infectives, M. A. Wuonola and D.G. Powers Application of Polymer-Supported Chemistry to the Discovery and Optimization of Lead Drug Candidates, A.L. Harris and B.E. Toyonaga Using Pharmacophore Diversity To Select Molecules To Test from Commercial Catalogues, K. DaviesPrice: $ Combinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of : Hardcover.

  Molecular Diversity and Combinatorial Chemistry emphasises principles and exemplifies these with examples drawn from recent literature and thus is an excellent guide to the conceptual framework of the Edition: 1. Reports progress on chemical, enzymatic, phage, and cell-derived libraries. Discusses synergy between structure-based design and combinatorial libraries. Presents applications of combinatorial libraries to drug discovery and new synthetic catalysis. Reports library screening approaches, including the use of NMR. Presents recent advances in solid-phase organic synthesis, liquid-phase organic. Molecular Diversity presents refereed papers describing the development, application and theory of molecular diversity, and combinatorial chemistry in basic and applied research and drug discovery. The journal publishes both short and full-length papers, perspectives, news and reviews. Combinatorial chemistry and molecular diversity approaches to scientific and novel product R & D have exploded in the s. For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds.

Molecular diversity and combinatorial chemistry: principles and applications. [Michael C Pirrung] -- Written for advanced undergraduate and graduate students, this textbook makes the main concepts of combinatorial chemistry accessible to the non-specialist. Combinatorial Chemistry and Molecular Diversity in Drug Discovery is one of the first comprehensive books to cover this explosive area. It is must reading for medicinal chemists, pharmacologists, molecular biologists, biochemists, enzymologists, and drug discovery research managers in industry, academia, and government. Compilations of literature in combinatorial chemistry, solid phase organic synthesis, solid phase peptide synthesis, library production and screening, automation and robotic synthesis and molecular diversity field. Listings of scientists and companies working in the field. Intractive areas for discussions, job listings and interesting site links. Molecular Diversity and Combinatorial Chemistry: Libraries and Drug Discovery; find Aldrich-Z MSDS, related peer-reviewed papers, technical documents, similar products & more at Sigma-Aldrich.